We enter the third decade of this millennium amid rising doubts, risks and worries about technology, markets, nationalism, democracy and the world order. The unqualified enthusiasm for them that we saw in the past two decades has given way to concerns about what their right dosage is, and what, if any, are the antidotes should we have willy-nilly overdosed on any of them. This is good. Societies that try to answer them truthfully and thoughtfully can expect to emerge stronger and more successful in 2030. For public policy, as for investors and value creators, the opportunities and risks lie at the intersection of technology, health, society and geopolitics.